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SFCA syringe filters use membranes made of a polymer called sulfone modified cellulose acetate (SFCA). SFCA is a type of cellulose acetate that has been modified to improve its filtration properties, particularly its flow rate and protein binding characteristics. These filters are commonly used in laboratory settings for various filtration applications due to their versatility and performance.

Here are some key features and applications of SFCA syringe filters:

  1. High Flow Rate: SFCA membranes typically offer fast filtration rates, allowing for quick processing of samples. This makes them suitable for applications where rapid filtration is desired.

  2. Low Protein Binding: SFCA membranes have minimal protein binding properties, which helps to minimize sample loss and ensure high recovery of proteins and other biomolecules. This makes them suitable for filtration of proteinaceous samples and biological fluids.

  3. Chemical Compatibility: SFCA syringe filters are compatible with a wide range of aqueous and organic solvents, acids, and bases. This broad chemical compatibility makes them versatile for various filtration applications in different laboratory settings.

  4. Sterilization: SFCA membranes can be used for sterilization of aqueous solutions and biological samples due to their ability to remove microorganisms such as bacteria and fungi.

  5. Clarification: They are effective for clarifying turbid samples by removing particulates, colloids, and other impurities. This makes them useful for sample preparation in analytical techniques such as HPLC (High-Performance Liquid Chromatography) and other analytical methods.

SFCA syringe filters are available in various pore sizes, typically ranging from 0.2 µm to 0.45 µm, allowing users to select the appropriate filter based on the size of particles they need to remove from their samples. They are widely used in research, pharmaceutical, biotechnology, and environmental laboratories for sample preparation, sterilization, and clarification purposes

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