Apurun Launches Comprehensive Nanoparticle Drug Products Manufacturing Platform and cGMP Development Services

Apurun Launches Comprehensive Nanoparticle Drug...

Apurun Announces Launch and Shipping of Its Comprehensive Nanoparticle Manufacturing Products & Services, Starting August 2024 Mountain View, CA, August 2024 – Apurun, a trailblazer in nanoparticle pharmaceuticals, proudly announces...

Apurun Launches Comprehensive Nanoparticle Drug...

Apurun Announces Launch and Shipping of Its Comprehensive Nanoparticle Manufacturing Products & Services, Starting August 2024 Mountain View, CA, August 2024 – Apurun, a trailblazer in nanoparticle pharmaceuticals, proudly announces...

Lipid nanoparticles utilizing nanoemulsion for enhanced delivery of demethylcantharidin targeting effective treatment of liver cancer

Lipid nanoparticles utilizing nanoemulsion for ...

Demethylcantharidin (DEM) is a commonly used antitumor drug, but its effectiveness is hindered by poor tumor targeting and significant organ toxicity. This study aimed to develop an innovative drug delivery...

Lipid nanoparticles utilizing nanoemulsion for ...

Demethylcantharidin (DEM) is a commonly used antitumor drug, but its effectiveness is hindered by poor tumor targeting and significant organ toxicity. This study aimed to develop an innovative drug delivery...

Modeling RNA Lipid Nanoparticle Transport: Quantum Mechanics and PBPK Approaches

Modeling RNA Lipid Nanoparticle Transport: Quan...

This study successfully developed a model to understand the transportation of RNA lipid nanoparticles (RNA-LNPs) across various species, including Hela cells, rats, mice, and humans, using physiologically based pharmacokinetic (PBPK)...

Modeling RNA Lipid Nanoparticle Transport: Quan...

This study successfully developed a model to understand the transportation of RNA lipid nanoparticles (RNA-LNPs) across various species, including Hela cells, rats, mice, and humans, using physiologically based pharmacokinetic (PBPK)...

Engineering Lipid-Mediated Delivery of Recombinant bioPROTACs for Efficient Intracellular Protein Degradation

Engineering Lipid-Mediated Delivery of Recombin...

Lipid-mediated intracellular delivery of recombinant #bioPROTACs for rapid degradation of #undruggableproteins has recently gained prominence in targeted degradation therapy. Utilizing 'event-driven' pharmacology, #proteolysistargetingchimeras (#PROTACs) offer superior efficacy compared to traditional...

Engineering Lipid-Mediated Delivery of Recombin...

Lipid-mediated intracellular delivery of recombinant #bioPROTACs for rapid degradation of #undruggableproteins has recently gained prominence in targeted degradation therapy. Utilizing 'event-driven' pharmacology, #proteolysistargetingchimeras (#PROTACs) offer superior efficacy compared to traditional...

Rapid Synthesis of Amidine-Integrated Degradable Lipids for Efficient and Versatile mRNA Delivery In Vivo

Rapid Synthesis of Amidine-Integrated Degradabl...

In this study, he synthesis of amidine-incorporated degradable (AID) lipids for mRNA delivery involves a novel and efficient method utilizing a one-pot, tandem multi-component reaction. This method employs amine, thiol,...

Rapid Synthesis of Amidine-Integrated Degradabl...

In this study, he synthesis of amidine-incorporated degradable (AID) lipids for mRNA delivery involves a novel and efficient method utilizing a one-pot, tandem multi-component reaction. This method employs amine, thiol,...

Transformative Role of Lipid Nanoparticles in Advancing CAR T Cell Therapy

Transformative Role of Lipid Nanoparticles in A...

Lipid nanoparticles (LNPs) have emerged as transformative agents in chimeric antigen receptor (CAR) T cell therapy, offering significant advantages over traditional methods. They address key challenges such as immunogenicity, reduced...

Transformative Role of Lipid Nanoparticles in A...

Lipid nanoparticles (LNPs) have emerged as transformative agents in chimeric antigen receptor (CAR) T cell therapy, offering significant advantages over traditional methods. They address key challenges such as immunogenicity, reduced...

Emerging Lipid-Based Nanoparticles for Colorectal Cancer Therapy: Challenges and Future Directions

Emerging Lipid-Based Nanoparticles for Colorect...

Lipid-based nanoparticles (LNPs), including solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), and polymeric lipid nanoparticles (PLNs), are promising for colorectal cancer (CRC) therapy due to their biodegradability, biocompatibility, reduced...

Emerging Lipid-Based Nanoparticles for Colorect...

Lipid-based nanoparticles (LNPs), including solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), and polymeric lipid nanoparticles (PLNs), are promising for colorectal cancer (CRC) therapy due to their biodegradability, biocompatibility, reduced...

Transforming Cells into Long-Lasting Drug Factories w/ Novel mRNA Techs

Transforming Cells into Long-Lasting Drug Facto...

A team of researchers at UT Southwestern Medical Center has pioneered a ribonucleic acid (RNA)-based method that enables in vivo cells to produce and secrete therapeutic proteins into the bloodstream....

Transforming Cells into Long-Lasting Drug Facto...

A team of researchers at UT Southwestern Medical Center has pioneered a ribonucleic acid (RNA)-based method that enables in vivo cells to produce and secrete therapeutic proteins into the bloodstream....

Machine Learning in Lipid Nanoparticle Drug Delivery Systems

Machine Learning in Lipid Nanoparticle Drug Del...

Machine Learning in Lipid Nanoparticle Drug Delivery Systems Machine learning (ML) is revolutionizing the development of Lipid Nanoparticle (LNP) drug delivery systems, providing new insights and enhancing the precision of...

Machine Learning in Lipid Nanoparticle Drug Del...

Machine Learning in Lipid Nanoparticle Drug Delivery Systems Machine learning (ML) is revolutionizing the development of Lipid Nanoparticle (LNP) drug delivery systems, providing new insights and enhancing the precision of...

Solvent Injection for Manufacturing of Nanomedicines Pharmaceuticals

Solvent Injection for Manufacturing of Nanomedi...

Solvent Injection for Manufacturing of Nanomedicines Pharmaceuticals Introduction The solvent injection method is a pivotal technique in the production of nanomedicines. This process entails the injection of a solvent, typically...

Solvent Injection for Manufacturing of Nanomedi...

Solvent Injection for Manufacturing of Nanomedicines Pharmaceuticals Introduction The solvent injection method is a pivotal technique in the production of nanomedicines. This process entails the injection of a solvent, typically...

Products
Achieve unparalleled precision with the Nanosizer Pro, engineered for high-throughput and exact particle size distribution—ideal for cutting-edge research and industrial applications.
Elevate your production capabilities with NanoSizer X’s state-of-the-art extrusion technology, designed to scale both research and GMP nanoparticle manufacturing.
The NanoSizer MINI Extruder is a compact, efficient tool designed for precise nanoparticle synthesis. Ideal for small-scale laboratory applications, it allows for exact control over particle size.
Apurun’s Lipid Polymer Hybrid Nanoparticles and Liposomes combine biocompatibility with the stability of polymer nanoparticles for optimized therapeutic delivery, suitable for both research and GMP.
Apurun's research-grade Lipid Nanoparticles encompass ionizable, cationic, and neutral varieties, providing a versatile toolkit for advanced drug delivery research.
Apurun provides comprehensive GMP documentation for Quality Assurance, Manufacturing, and Quality Control, ensuring consistent compliance and high-quality product standards across all phases of production.
Apurun offers high-quality lipids tailored for diverse pharmaceutical and biotechnological applications, ensuring optimal performance and reliability.
Apurun's advanced polymers are designed for innovative drug delivery systems, enhancing efficacy and safety through controlled release and targeted delivery technologies.
Apurun offers a comprehensive selection of literature and books, providing valuable insights into the latest advancements in nanoparticle technology and applications.
Apurun provides comprehensive analytical services, offering detailed assessments and validations across a full spectrum of tests to ensure the integrity and effectiveness of pharmaceutical products.
Apurun offers ready-to-use nanoparticle reagents designed for streamlined development and testing, significantly reducing preparation time and enhancing research productivity.
Apurun provides advanced filtration solutions tailored for the post-processing and sterile manufacturing of nanoparticle pharmaceuticals, ensuring purity and compliance with stringent industry standards.