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Apurun

cKK-E12 (Ionizable Lipid)

cKK-E12 (Ionizable Lipid)

Regular price $187.00 USD
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Ionizable lipids, in combination with other lipids, form lipid nanoparticles essential for delivering RNA-based therapeutics. cKK-E12 has demonstrated effective delivery of siRNA in mice, rats, and primates, with respective ED50 values of 0.002, 0.01, & 0.3 mg/kg. It exhibits low toxicity and preferential targeting of liver parenchymal cells over liver, heart, lung, and kidney endothelial cells. This product is exclusively for research purposes and not intended for human use

Chemical Specifications

  • CAS Number: 1432494-65-9
  • Molecular Formula: C60H120N4O6
  • Molecular Weight: Approximately 993.64 g/mol
  • Purity: 0.95

Physical and Chemical Properties

  • Solubility: Chloroform, methanol, ethanol
  • Storage: Store dry at 4°C or below. Stock solutions should be stored at -20°C.
  • Shipping Temperature: Gel Ice

Background

Cationic lipids, when combined with other lipids, form lipid nanoparticles for delivering RNA-based therapeutics. cKK-E12 has been successfully utilized to deliver siRNA in mice, rats,

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