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DPPC (16:0-16:0 PC)

DPPC (16:0-16:0 PC)

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DPPC

DPPC (1,2-Dipalmitoyl-sn-glycero-3-phosphocholine): DPPC is a phospholipid commonly used in liposome research and drug delivery applications. It is a zwitterionic lipid, meaning it carries both a positive and a negative charge within the same molecule, which contributes to its stability and biocompatibility.

Chemical Specifications:

CAS Number 63-89-8
Molecular Formula C40H80NO8P
Molecular Weight (g/mol) Approx. 734.04
Purity >99%

Physical and Chemical Properties:

Appearance White to off-white solid
Solubility Insoluble in water, soluble in organic solvents
Melting Point Approx. 41-42°C
Boiling Point Not applicable (decomposes)
Density Approx. 1.01 g/cm³
pH Neutral
Stability Stable under normal conditions
Reactivity Non-reactive with common chemicals

Storage and Handling:

Storage Store in a cool, dry place at -20°C or below
Handling Handle with gloves and avoid inhalation or ingestion. Protect from moisture and light.

DPPC is widely used in the pharmaceutical industry for its role in drug delivery systems, particularly in liposomal formulations. It serves as a major component of liposomes, which are spherical vesicles composed of lipid bilayers. These liposomes can encapsulate drugs or other therapeutic agents and deliver them to target tissues or cells. DPPC's biocompatibility and stability make it an ideal choice for such applications.

Additionally, DPPC is extensively studied in biophysical research due to its ability to form stable bilayers and mimic biological membranes. Its properties are often investigated using techniques such as differential scanning calorimetry (DSC) and nuclear magnetic resonance (NMR) spectroscopy to understand its behavior in lipid membranes and its interactions with other molecules.

Overall, DPPC plays a crucial role in various fields, ranging from drug delivery and biotechnology to fundamental studies of membrane structure and function.

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